Rotavirus Vaccines in Routine Use

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Rotavirus vaccines in routine use.

Vaccines are now available to combat rotavirus, the most common cause of severe diarrhea among children worldwide. We review clinical trial data for available rotavirus vaccines and summarize postlicensure data on effectiveness, impact, and safety from countries routinely using these vaccines in national programs. In these countries, rotavirus vaccines have reduced all-cause diarrhea and rotavi...

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BACKGROUND Rotavirus results in higher diarrhoea-related death in children less than five years of age than any other single agent, particularly in low- and middle-income countries. The World Health Organization has recommended the use of rotavirus vaccines in childhood immunization schedules. OBJECTIVES To evaluate rotavirus vaccines approved for use (Rotarix, RotaTeq, and Lanzhou Lamb Rotav...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2014

ISSN: 1058-4838,1537-6591

DOI: 10.1093/cid/ciu564